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Table 1 A partial list of commonly used database search software tools for proteomics analysis

From: Recent advances in proteomics and metabolomics in plants

Software name

Latest version

Source availability

Developer

URL and references

Proteome Discoverer

2.5

proprietary

Thermo Scientific

https://www.thermofisher.com/order/catalog/product/OPTON-30810

ProteinPilot

5.0.2

proprietary

Sciex

https://sciex.com/products/software/proteinpilot-software

ProteinLynx Global Server

3.0.3

proprietary

Waters

https://www.waters.com/waters/en_US/ProteinLynx-Global-SERVER-(PLGS)/nav.htm?cid=513821&locale=en_US

PaSER

2022

proprietary

Bruker

https://www.bruker.com/en/products-and-solutions/mass-spectrometry/ms-software/paser

MassHunter

11.0

proprietary

Agilent

https://www.agilent.com/en/product/software-informatics/mass-spectrometry-software/data-analysis

MASCOT

2.8

proprietary

Matrix Science Inc

https://www.matrixscience.com/server.html; (Perkins et al. 1999)

MaxQuant

2.0.3.0

Freeware

Max Planck Institute of Biochemistry

https://www.maxquant.org/; (Cox and Mann 2008)

Byonic

4.2

proprietary

Protein Metrics Inc

https://proteinmetrics.com/byos/; (Bern et al. 2007)

Scaffold

5.1.0

proprietary

Proteome Software, Inc.

https://www.proteomesoftware.com/products/scaffold-5;(Searle 2010)

MSFragger

3.4

Freeware

University of Michigan

https://www.nesvilab.org/software.html;(Kong et al. 2017)

OMSSA

2.1.19

Freeware

The NIH intramural research program

https://ftp.ncbi.nlm.nih.gov/pub/lewisg/omssa/;(Geer et al. 2004)

Phenyx

Phenyx ®

proprietary

Geneva Bioinformatics (GeneBio)

https://ionsource.com/functional_reviews/Phenyx/phenyx-web.htm; (Colinge et al. 2003)

PRAKS DB

Xpro

proprietary

Bioinformatics Solutions Inc.

https://www.bioinfor.com/;(Zhang et al. 2012)

Protein Prospector

6.3.1

open source

University of California, San Francisco

https://prospector.ucsf.edu/prospector/mshome.htm;(Chalkley et al. 2005)

X!Tandem

2017.02.01

open source

University, Ghent, Belgium

http://www.thegpm.org/TANDEM/index.html;(Muth et al. 2010)