Fig. 1

Structures of auxin- and NPA-bound PIN1 protein. A Chemical structures of the natural auxin IAA and the synthetic inhibitor NPA. B Structures of IAA- and NPA-bound PIN1 protein. Left, IAA-bound PIN1 structure (PDB accession code: 7Y9V). Right, NPA-bound PIN1 structure (PDB accession code: 7Y9U, Yang et al. 2022). PIN1 protein is shown in a cartoon mode and colored light blue. IAA and NPA molecules are shown in spheres, with carbon atoms colored blue and red, respectively